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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP25
All Species:
19.39
Human Site:
S479
Identified Species:
47.41
UniProt:
Q9UHP3
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UHP3
NP_037528.3
1087
125750
S479
I
D
A
S
S
P
P
S
G
S
I
P
S
Q
T
Chimpanzee
Pan troglodytes
XP_531393
1087
125791
S479
I
D
A
S
S
P
P
S
G
S
I
P
S
Q
T
Rhesus Macaque
Macaca mulatta
XP_001107973
1166
134796
S558
I
D
A
S
S
P
P
S
G
S
I
P
S
Q
T
Dog
Lupus familis
XP_535562
1085
125476
S479
I
D
A
S
S
P
P
S
G
S
T
P
Q
T
L
Cat
Felis silvestris
Mouse
Mus musculus
P57080
1055
121402
S479
I
D
A
S
S
S
A
S
G
P
L
P
S
Q
S
Rat
Rattus norvegicus
NP_001100584
1055
121573
S480
I
D
A
T
S
S
T
S
G
S
T
S
S
Q
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514451
1105
126985
E529
P
V
C
T
S
P
V
E
D
I
D
A
A
A
P
Chicken
Gallus gallus
Q5ZID5
1047
118729
Q466
V
S
S
T
E
D
S
Q
M
M
D
R
Q
S
Q
Frog
Xenopus laevis
NP_001086746
1046
121273
I471
C
T
S
P
V
E
D
I
D
V
S
A
P
P
S
Zebra Danio
Brachydanio rerio
NP_001001886
1072
123104
G479
I
D
T
T
A
P
P
G
G
T
I
A
Q
L
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
92.2
97.5
N.A.
91.1
91.5
N.A.
81.5
46.8
79.3
74.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.8
92.8
98.8
N.A.
93.7
94.1
N.A.
86.7
64.1
86.8
84.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
73.3
N.A.
66.6
60
N.A.
13.3
0
0
40
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
73.3
N.A.
80
73.3
N.A.
26.6
20
13.3
60
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
60
0
10
0
10
0
0
0
0
30
10
10
0
% A
% Cys:
10
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
70
0
0
0
10
10
0
20
0
20
0
0
0
0
% D
% Glu:
0
0
0
0
10
10
0
10
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
10
70
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
70
0
0
0
0
0
0
10
0
10
40
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
10
0
0
10
10
% L
% Met:
0
0
0
0
0
0
0
0
10
10
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
0
0
10
0
60
50
0
0
10
0
50
10
10
20
% P
% Gln:
0
0
0
0
0
0
0
10
0
0
0
0
30
50
10
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% R
% Ser:
0
10
20
50
70
20
10
60
0
50
10
10
50
10
30
% S
% Thr:
0
10
10
40
0
0
10
0
0
10
20
0
0
10
30
% T
% Val:
10
10
0
0
10
0
10
0
0
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _